ICDSUPL1-T008

Volume: 1, 2022
1^st International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: ENVIRONMENT  – PLANT  – ANIMAL  – PRODUCT

Abstract number: T008

DOI: https://doi.org/10.24326/ICDSUPL1.T008

Published online: 26 April 2022

ICDSUPL, 1, T008 (2022)

Use of plant-based lipase inhibitors in the prevention of obesity

Paula Grdeń¹*, Adam S. Grdeń², Anna Jakubczyk¹

^{1 Department of Biochemistry and Food Chemistry, Faculty of Food Science and Biotechnology, University of Life Sciences in Lublin; Skromna 8, 20-704 Lublin, Poland}

^{2 Department of Dairy Technology and Functional Foods, Faculty of Food Science and Biotechnology, University of Life Sciences in Lublin; Skromna 8, 20-704 Lublin, Poland}

^{* Correspondence author: paula.cwiek@up.lublin.pl}

Abstract

The problem of excessive body weight, which is overweight and obesity, affects around 1.9 billion people worldwide, with almost 3.4 million people dying from it in 2014. Unfortunately, despite many prevention and education programmes, the number of overweight and obese people, including children, continues to rise. Obesity is one of the factors which increase the risk of many diseases, including type 2 diabetes, hypertension and cancer. This is why prevention and treatment of this disease is so important. The main method used to both prevent and treat obesity is a well-balanced diet rich in vegetables, fruit, unsaturated fatty acids and complete protein. However, one of the methods of pharmacotherapy for people with obesity is the inclusion of preparations containing inhibitors of pancreatic lipase, which is responsible for breaking down most fats from food and releasing fatty acids, the excess of which is accumulated in the form of adipose tissue. Inhibiting the activity of this enzyme limits the absorption of fatty acids in our body. Unfortunately, pharmacological preparations containing pancreatic lipase inhibitors can cause serious side effects. Properties inhibiting pancreatic lipase are demonstrated, among others, by polyphenols and bioactive peptides contained in many fruits, vegetables, pulses and cereals. This gives a potential opportunity to use them in planned diet therapy. The use of products rich in pancreatic lipase inhibitors in the diet of people suffering from obesity or overweight may improve the effects of pharmacotherapy and diet therapy of these diseases and not cause side effects.

How to cite

P. Grdeń, A.S. Grdeń, A. Jakubczyk, 2022. Use of plant-based lipase inhibitors in the prevention of obesity. In: 1st International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL1/T008