Volume: 2, 2023
2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland:
ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: A020
DOI: https://doi.org/10.24326/ICDSUPL2.A020
Published online: 19 April 2023
ICDSUPL, 2, A020 (2023)
Effect of feeding diet containing coccidiostat and administration of antibiotics to turkeys in the first days after hatching on blood levels of selected hormones
Katarzyna Nadolna1*, Anna Stępniowska2, Katarzyna Ognik2, Dariusz Mikulski1, Krzysztof Kozłowski1, Jan Jankowski1
1 Department of Poultry Science and Apiculture, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, Poland
2 Department of Biochemistry and Toxicology, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland
* Corresponding author: katarzyna.nadolna@uwm.edu.pl
Abstract
The aim of the study was to determine the effect of early administration of an antibiotic, especially with a diet containing a coccidiostat, on the level of selected hormones in the blood serum of turkeys. The experiment was conducted on 1152 one-day-old turkeys divided into 6 treatments: CM(–), EM(–), DM(–), CM(+), EM(+), DM(+). Turkeys in the M(–) groups did not receive monensin in the diet, while those in the M(+) groups received monensin at a dose of 90 mg/kg of feed. Turkeys in groups C, received no antibiotic supplement (control groups), while those in groups E received enrofloxacin at a dose of 10 mg/kg BW for the first 5 days of life, and those in groups D received doxycycline at a dose of 50 mg/kg BW for the first 5 days of life. The birds were vaccinated against APV and NDV on day 1 of life and against ORT on day 28 of life. On days 7 and 56, blood was collected from 8 birds in the group to evaluate NA (noradrenaline), T4 (thyroxine), HIS (histamine), DOPA (dopamine), 5-HT (serotonin) levels. The conducted studies showed no effect of feeding turkeys with a diet containing monensin or early administration of enrofloxacin or dopamine on the level of NA and 5-HT in the blood serum of 7- and 56-day-old turkeys. The study shows that early administration of doxycycline to turkeys reduced the level of T4 in the blood serum of 7-day-old turkeys. On the other hand, early administration of enrofloxacin caused a distant effect, as it resulted in a decrease in the level of histamine in the blood serum of 56-day-old turkeys. Feeding turkeys with a diet containing the coccidiostat monensin resulted in an increase in dopamine levels in the blood serum of 7-day-old turkeys, and after prolonged administration of monensin – on the 56th day of turkeys life, increased levels of histamine and dopamine in the blood serum were found. The research shows that long-term administration of the coccidiostat monensin increases the level of biogenic catecholamine (dopamine), and when the level of dopamine increases periodically, the sensitivity of dopamine receptors decreases. With increased levels of dopamine, the body is less sensitive to stress reactions. However, an increase in the level of histamine is unfavorable because it can lead to vasodilation, and consequently to a drop in blood pressure, increased secretion of bile and gastric juice. The above reactions may result in diarrhea in birds. Feeding turkeys with a diet containing the addition of monensin, as well as early administration of the antibiotic doxycycline or enrofloxacin, adversely affects the hormonal balance of birds.
This work was supported by the National Science Centre in Poland, Grant No. 2020/39/B/NZ9/00765.
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How to cite
K. Nadolna, A. Stępniowska, K. Ognik, D. Mikulski, K. Kozłowski, J. Jankowski, 2023. Effect of feeding diet containing coccidiostat and administration of antibiotics to turkeys in the first days after hatching on blood levels of selected hormones. In: 2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL2.A020