Volume: 2, 2023
2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland:
ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: B010
DOI: https://doi.org/10.24326/ICDSUPL2B010
Published online: 19 April 2023
ICDSUPL, 2, B010 (2023)
Stenotrophomonas maltophilia – review of knowledge
Bartosz Niemiec1*, Bruno Olesiński1, Zuzanna Guzowicz1, Monika Cendrowska-Pinkosz2, Mateusz Szymański3
1 Student Scientific Group, Department of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-900 Lublin, Poland
2 Department of Human Anatomy, Medical University of Lublin, 4 Jaczewski Street, 20-090, Lublin, Poland
3 Department of Anesthesiology, Stefan Wyszyński Regional Specialist Hospital, Lublin, Poland
* Corresponding author: bartoszn1999@gmail.com
Abstract
Stenotrophomonas Maltophilia is a Gram-negative opportunistic pathogen of significant prelevance and a reason to concern about susceptible patients. This bacteria causes mostly nosocomial but also community-acquired respiratory tract and bloodstream infections and various other infections in humans. Water, plant rizosphere, food and animals are examples of sources. S. Maltophilia virulence factors are include motility, biofilm formation, cell-density-dependent quorum sensing, however they are still being explored. Another important virulence factor is it’s multidrug resistance against antimicrobial drugs such as: cotrimoxazole, β-lactams including carbapenems and cephalosporins, macrolides, fluoroquinolones, aminoglycosides, chlopramphenicol, tetracyclines and polymixines. Current treatment standards recognize treatment with TMP-SMX (trimethoprim-sulfamethoxazole), quinolones, penicillins and penicillins with β-lactamase inhibitors as most effective. Fast diagnosis is a important factor for succesfull treatment, therefore new methods of detecting this bacteria are being developed. As a result new type of medium – selective steno medium agar and new ways to detect pathogen’s nucleic acid are being researched. Patients infected with this bacteria are more likely to develop co-infections with other gram-negative bacteria. The study conducted on cancer patients between 1986 and 2002 showed a rise of S. Maltophilia infections from 2% to 7% and classified it as a 5th most commonly isolated G-negative bacteria among those patients. Most commonly this bacteria infects the ICU (Intensive Care Unit) patients and patients with Sars-CoV-2 infection with pneumonia as the most frequent manifestation. The COVID-19 pandemic increased the number of ICU patients treated by mechanical ventillation, which resulted in higher infection rate of S. Maltophilia.
How to cite
B. Niemiec, B. Olesiński, Z. Guzowicz, M. Cendrowska-Pinkosz, M. Szymański, 2023. Stenotrophomonas maltophilia – review of knowledge. In: 2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL2B010