Volume: 3, 2024
3rd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland:
ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: F020
DOI: https://doi.org/10.24326/ICDSUPL3.F020
Published online: 24 April 2024
ICDSUPL, 3, F020 (2024)
(Bio)polymeric particles for agents’ encapsulation to achieve active systems for various applications
Michal Kolař1*, Barbora Včelikova1, Soňa Hermanova1
1 FoodTech, Faculty of AgriSciences, Mendel University in Brno, Zemědělska 1665/1, 61300, Brno, Czech Republic
* Corresponding author: xkolar6@mendelu.cz
Abstract
Bio-based materials have great potential as carriers for various cargo transport and its controlled release. Thanks to encapsulation and/or entrapment within the matrix of a carrier material, it is possible to add active agent into these materials to control the release of the active substance. Encapsulation is an advanced modern technique of agent modification that has widespread use in the food industry, agriculture, or medicine. It can be used to protect sensitive compounds against degradation or to mask the bitter taste of API or a supplement and provide controlled and targeted release of the active substance. In this study, phytochemicals, and model dyes, such as curcumin, and Nile red, respectively, were incorporated into biodegradable and biopolymeric materials (polycaprolactone, sodium alginate) under various conditions. Sodium alginate-based carriers with active agents were prepared from 1, 2.5, and 5% aqueous solution. These systems were achieved by water/oil (W/O) emulsion methods in the form of capsules and wires with quantitative efficiency. Resulting carrier systems were subjected to optical microscopy and spectrophotometric techniques (UV-vis analysis). The particle size and particle/wire morphology were determined via optical microscopy. Prepared capsules (1, 2.5, 5%) were spherical in nature with diameters ranging from 1 400 to 2 950 μm while higher concentration of alginate capsules (5%) formed more irregular shape due to viscosity of the solution. Encapsulation efficiency was determined via UV-vis spectrophotometry and calibration curve method for the concentration ranges 20–185, 2.5–12.5 μg/mL for curcumin, and Nile red respectively. The prepared (bio)polymeric particles will serve as model carriers for active agents for further understanding of components interactions.
Keywords: encapsulation, controlled release, phytochemicals
How to cite
M. Kolař, B. Včelikova, S. Hermanova, 2024. (Bio)polymeric particles for agents’ encapsulation to achieve active systems for various applications. In: 3rd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL3.F020