Volume: 2, 2023
2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland:
ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: B007
DOI: https://doi.org/10.24326/ICDSUPL2B007
Published online: 19 April 2023
ICDSUPL, 2, B007 (2023)
The effects of caffeine consumption on chosen biochemical parameters of the pregnant female rats
Zuzanna Guzowicz1*, Bartosz Niemiec1, Bruno Olesiński1, Monika Cendrowska-Pinkosz2
1 Student Scientific Group, Department of Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-900 Lublin, Poland
2 Department of Human Anatomy, Medical University of Lublin, 4 Jaczewski Street, 20-090, Lublin, Poland
* Corresponding author: zguzowicz@gmail.com
Abstract
There are various adaptive changes in the female body during pregnancy. The adjustments occurring in the mother’s body throughout this period are necessary for the correct development of their offspring. Those adjustments can be influenced and oftentimes disturbed by the intake of substances with proven unfavorable effects on the body. Caffeine is one of the most chronically used xenobiotics. It is present in many comestible products and pharmaceuticals. Due to the wide range of applications caffeine can be consumed in various temperature ranges. It was assumed that the temperature of consumed caffeine might influence certain biochemical parameters in the serum of pregnant females. General aim of the study was to evaluate the influence of caffeine at given temperatures on chosen biochemical parameters of renal function in pregnant female rats. The study was performed on pregnant female rats from 8th to 21st day of pregnancy. During the study pregnant female rats were orally administered a solution of caffeine in temperatures 10, 25 and 45 C once a day. At the end of the study parameters such as Creatinine (CREAT), urea (UREA) and ureic acid (UA) were marked in the serum. The results showed increased levels of UA and UREA in the serum of animals who received caffeine compared with animals from the control group. Moreover, it was confirmed that the administration of caffeine has a negative impact on the regulation of CREAT and UREA in pregnant female rats. Lastly, the temperature of the administered caffeine did not influence the concentration of the analyzed biochemical parameters.
How to cite
Z. Guzowicz, B. Niemiec, B. Olesiński, M. Cendrowska-Pinkosz, 2023. The effects of caffeine consumption on chosen biochemical parameters of the pregnant female rats In: 2nd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL2B007