Volume: 5, 2026
5th International PhD Students’ Conference at the University of Life Sciences in Lublin, Poland:
ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: H021
DOI: https://doi.org/10.24326/ICDSUPL5.H021
Published online: 22 April 2026
Comparative analysis of heparin and heparan sulfate in surface modification
Katarzyna Wojdat
Department of Interfacial Phenomena, Institute of Chemical Sciences Maria Curie-Skłodowska University in Lublin, 3 Maria Curie-Skłodowska Sq., 20-031 Lublin, Poland
Corresponding author: katarzyna.wojdat@mail.umcs.pl
Glycosaminoglycans are organic compounds belonging to the polysaccharide group, composed of amino sugars and iduronic or glucuronic acid residues. The presence of these acids results in a high negative charge density, because they contain sulfate and carboxyl groups. Additionally, the sulfate groups are responsible for the anticoagulant properties of some glycosaminoglycans. Examples of such compounds include heparin and heparan sulfate. What is more, some GAGs have antibacterial properties. Coatings made from these compounds applied to biomaterial surfaces can serve various functions. Heparin coatings enhance the biocompatibility of materials and can be utilized as drug delivery systems. However, heparan sulfate forms a characteristic “brush-like” structure on the surface, which enables the control of cell adhesion and the study of cell migration. Both of these compounds have broad application potential in biomaterial engineering.
Keywords: biomaterials; glycosaminoglycans; heparan sulfate; heparin
How to cite
Wojdat K., 2026. Comparative analysis of heparin and heparan sulfate in surface modification. In: 5th International PhD Students’ Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL5.H021