Volume: 1, 2022
1st International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: ENVIRONMENT – PLANT – ANIMAL – PRODUCT
Abstract number: T047
DOI: https://doi.org/10.24326/ICDSUPL1.T047
Published online: 26 April 2022
ICDSUPL, 1, T047 (2022)
Diet therapy of obesity and type 2 diabetes, including lactoferrin fortified yoghurts
Anna Jańczuk1*
1 Department of Quality Assessment and Processing of Animal Products, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences; Akademicka 13, 20-950, Lublin, Poland
* Corresponding author: annajanczuk44@gmail.com
Abstract
Lactoferrin is a multipotent bioactive protein. It supports the functioning of the immune system, reduces oxidative stress, and also limits weight gain during a high-fat diet. It occurs naturally, incl. in milk, therefore including this raw material and dairy products in the diet is the simplest form of its supply to the body. The research aimed to evaluate the effectiveness of the produced lactoferrin-fortified yogurt and to develop a diet therapy pattern including lactoferrin-fortified yogurt in obesity and type 2 diabetes. As part of the research, natural yogurts fortified with lactoferrin were produced and used in the diets of overweight and obese people. The evaluation of effectiveness of lactoferrin-enriched yogurt in reducing overweight and obesity was assessed in a crossover study. Yogurt with and without added lactoferrin (80 mg) was administered to volunteers once a day in an amount of 100 g for 28 days. The criteria for enrollment in the studies were the body mass index BMI (> 26 kg / m2) and WHtR index (> 52). Moreover, the subjects included in the study had a risk variant (homozygous or heterozygous) of single nucleotide polymorphisms: rs9939609, rs1121980, rs7903146, rs10830963. 11 women and 8 men were included in the study. The Polish population differs in terms of the frequency of the individual determining single nucleotide polymorphisms from the European population described in the databases of the “HapMap” and “1000 Genomes” projects. In a cross-over study, carried out on a 21-day cycle, the study group and the 7-day control group, and the 7-day control and 21-day study group, there was no statistically significant effect of the previous consumption of yogurt without lactoferrin on the rate of weight loss after starting yogurt with lactoferrin. After 21 days of consuming yogurt with lactoferrin, statistically significant improvement in the following parameters was observed: body weight, adipose tissue content, HOMA-IR, and glycosylated hemoglobin. Summing up, it should be stated that dairy products, as a natural source of lactoferrin, but also lactoferrin supplementation, should be included in the diet of people with obesity and type 2 diabetes.
How to cite
A. Jańczuk, 2022. Diet therapy of obesity and type 2 diabetes, including lactoferrin fortified yoghurts. In: 1st International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: Environment – Plant – Animal – Product. https://doi.org/10.24326/ICDSUPL1/T047